Current Research Projects:

Dietary Methionine Restriction as a Therapeutic Strategy for Metastatic Melanoma
– Thematic Area: Methionine and Epigenetics
– PI: Dr. Isabelle Racine-Miousse

The Role of Phosphorylation of Isocitrate Dehydrogenase in Breast Cancer
– Thematic Area: Protein Chemistry and Protein Engineering
– PI: Dr. Chenguang Fan

Unraveling Gene-Environment Interactions Shaping Metabolism: A Multi-Omics Analysis in Drosophila
– Thematic Area: Metabolic Disease and Genetic Variation
– PI: Dr. Xuan Zhuang

Investigating the Bioenergetics of Tumor Cell Clustering and Cell-Cell Interactions
– Thematic Area: Using engineering, biology, and computation approaches to understand the mechanobiology of cancer, with a specific focus on cancer mechano-metabolism.
– PI: Dr. Jian Zhan

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Prior Research Projects:

The Role of Altered Glutamine Metabolism in Breast Tumor Innervation and its Connection to Brain Metastasis
– Thematic Area: Biomaterials, tumor microenvironment, stem cells, regenerative medicine
– PI: Dr. Younghye Song

Epigenome Engineering for Precise Genetic Perturbation of Skeletal Muscle Gene Expression and Metabolism
– Thematic Areas: 1) Developing biologically inspired strategies for controlled drug and gene delivery for gene therapy and regenerative medicine; 2) Using molecular biology techniques to study muscle mass regulation in the contexts of exercise adaptation, aging, and disease.
– PIs: Drs. Christopher Nelson and Kevin Murach

Control of Epithelial Morphology and Bioenergetics by Toll Receptors During Dynamic Tissue Remodeling
– Thematic Area: How epithelial cells encode and communicate spatial cues to control cell shape and tissue morphology.
– PI: Dr. Adam Paré